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enamel-GEN

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enamel-GEN

Your enamel is thinning - and toothpaste can't stop it.

Real repair starting with your first use.

The first over-the-counter serum with 30% rod nano-hydroxyapatite, the exact mineral your enamel is made of. Not a coating. Not a rinse. A structural repair that works from your first use.

  • ✅ Fills microcracks where cavities start
  • ✅ Sensitivity relief from first application
  • ✅ 24/7 anti-plaque bacteria defense
  • ✅ Balances microbiome
  • ✅ Fluoride-free, non-toxic, safe if swallowed

If you’ve noticed that "not quite right" feeling, it's your enamel.

Stop losing it. Start rebuilding it with the most concentrated nano-hydroxyapatite formula available.

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$79.90
$119.98
Save $40.08

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365-Day Guarantee

365-DAY GUARANTEE

Doctor Formulated

DOCTOR FORMULATED

3X Action

3X ACTION

AS SEEN ON:

AS SEEN ON:

Doctor Formulated, Trusted by Experts, Loved by Thousands

Doctor Formulated, Trusted by Experts, Loved by Thousands

“I suggest enamel-GEN because its core mineral (hydroxyapatite) makes up 97% of what teeth are made of. Unlike regular toothpaste, the triple-action formula helps remineralize enamel, strengthen teeth, and provide long-lasting protection without temporary fixes.

After conducting over 2,000 clinical trials, I've seen firsthand how damaged enamel silently affects millions of people. That's why I helped develop enamel-GEN. A mineral based formula that doesn't just help sensitivity, it repairs the enamel itself.”

Joel M. Neutel, MD

Medical Director and Principle Investigator Orange County Research Center

Get Stronger Teeth Today

HOW IT WORKS

Activate
1

Activate

The "pH Flip" triggers an instant reaction in your mouth. Arginine Bicarbonate spikes oral pH to 8.5+ to neutralize cavity-causing acids and unlock enamel "absorption gates."

Repair
2

Repair

Our 30% Nano-hydroxyapatite (nHAp) Suspension Matrix creates a nutritive "micro-mask" that clings to teeth 50x longer than thin liquids, allowing heavy mineral particles to dock and seal lost density.

Protect
3

Protect

A Bacteria Blockade using 10% Xylitol and Zinc Gluconate to starve harmful bacteria and prevent plaque adhesion, while nano-hydroxyapatite (nHAp) fills the microscopic pits where they hide.

enamel-GEN vs. The Rest

Stop settling for surface-level cleaning. Give your teeth the professional-grade restoration they deserve.
enamel-GEN
Toothpaste
Structural Repair
Long-Lasting Pain Relief
24/7 Protection
Smart Bacteria Defense
100% Non-Toxic
Triple-Action Matrix

Rebuilds Enamel Naturally

Restores weak enamel, making your teeth stronger and acid-resistant

Stops Sensitivity Fast

Instantly relieves sensitivity and targets the source of tooth pain

Strengthens Teeth Daily

Improves tooth strength, reducing the risk of damage
Product

Protects Against Cavities

Helps defend your teeth from decay and daily wear

Anti-Plaque

Antimicrobial, slows plaque growth and buildup

Balanced Oral Microbiome

Supports a healthy microbiome by feeding good bacteria and eliminating bad bacteria

What To Expect

WEEK 1

Sensitivity Relief

Tubules and nerve endings are sealed by remineralization. Formula begins working at your very first use.
WEEK 2

Caries Filling In

Nano-mineral particles penetrate and repair weak areas. White spots fade as early-stage cavities begin reversing.
WEEK 3

Visible Changes

Enamel becomes noticeably thicker and stronger. Natural whitening and brightening begin to show.
WEEK 4+

Stronger Enamel

Continued remineralization supports long-term health. Dentists report visibly brighter and healthier teeth.
Clinical Transparency

Clinical Transparency

Most brands hide their percentages. We lead with ours.
30%

Nano-Hydroxyapatite

Enamel Repair Active
10%

Xylitol

Anti-Cavity / Saliva Boost
8%

Arginine Bicarbonate

pH Buffer & Relief
NO FLUORIDE. NO SLS.
NO ARTIFICIAL COLORS.
NO HARSH ABRASIVES.
View Clinical Studies & Research
The Restoration Protocol

3 Easy Steps

01

Prep

Brush and floss to ensure a clean surface. Removing surface plaque allows the nano-hydroxyapatite (nHAp) to make direct contact with your enamel.

02

Apply

Apply one full dropper of enamel-GEN to your teeth. Alternatively, place the serum on your toothbrush and apply. Allow to sit on the tooth's surface for 3 minutes.

03
Restore: 30 Minute Wait

Restore

Spit serum after 3 minutes. Do not rinse, eat, or drink for at least 15 minutes (30 minutes for best results). This allows the nano-hydroxyapatite (nHAp) to physically bond to your teeth.

Expert Tip

Optimize for Nightly Repair: Apply enamel-GEN immediately before bed. Salivary flow decreases while you sleep, creating an undisturbed environment for faster mineral restoration.

What People Are Saying

The Proof in the Formula

Real Results.
Visible Restoration.

94%
of Users Reported
Significant Relief
30 Days
To Visible
Mineral Restoration
24/7
Anti-Plaque
Defense Shield
Results Restoration

Frequently Asked Questions

How does it work?

The unique mixture of Nano-Hydroxyapatite, Arginine Bicarbonate, Zinc and Xylitol combines to balance mouth pH, kill unwanted bacteria, attack plaque cells, and give your teeth the nutrients they need to begin restoring enamel and repairing everyday damage.

How long does it take to get results?

Results vary from person to person. It's not uncommon to feel a difference after the first use and begin feeling less sensitivity immediately. Full remineralization begins within 2 weeks and continues over 90 days of consistent use. 

How do I do a “treatment”?

This process is very simple and can easily be added to your daily oral care routine. 

  1. Shake well 
  2. Apply 1 full dropper (1 mL) directly onto teeth 
  3. Swish to fully coat teeth or gently use toothbrush to evenly coat teeth
  4. Once applied, leave in mouth for 3 minutes
  5. Spit to dispose of used serum
  6. Wait at least 15 minutes before eating or drinking (30 minutes for best results) 

For best results, use twice daily, morning and evening, after brushing.

Safe and non-toxic if accidentally swallowed.

Is enamel-GEN guaranteed?

We stand behind enamel-GEN 100%. If you're not happy with your results for any reason, just reach out within 365 days of receiving your order and we'll issue a full refund. Email us at wecare@basisoral.com with your order number and our team will take care of you within 7 business days.

Is enamel-GEN safe?

Yes, enamel-GEN is non-toxic. Every ingredient is research-tested for safety and efficacy in oral care. 

How long does one bottle of enamel-GEN last?

With proper use each bottle should last 30 days. Each bottle contains 60 mL (60 applications). For best results, use twice daily.

If I already have a cavity, will enamel-GEN fix it?

While this varies from person to person, some users have reported feeling their cavities start to heal over in about 2 weeks to 90 days. enamel-GEN supports this process by providing your teeth with the nutrients they need to begin the healing process from within.

Can enamel-GEN help sensitive teeth?

Sensitive teeth are caused by the tubules in your teeth (microscopic tubes that lead to your nerves) being exposed when enamel wears away, which means hot and cold air and liquids can get right to your nerve. And this hurts! enamel-GEN helps sensitive teeth by rebuilding enamel to keep your tubules protected, which stops anything from reaching the nerves and prevents those sharp shooting pains.

How do I store my product?

enamel-GEN is bottled in sterile, non-reactive glass.

Improper storage in hot, humid, or sunny conditions can accelerate spoilage. We recommend that you:

  • Store product at room temperature
  • Avoid refrigeration
  • Avoid direct sunlight
  • Avoid excessive heat
  • Close cap tightly between uses
  • Avoid touching the dropper to any surface or letting it come into contact with hands or contaminants
Some of the reviews shown are from related products the merchant grouped with this one.
J
Jason W.

THIS STUFF IS AMAZING, I'VE GOT MY WHOLE FAMILY USING ENAMEL-GEN NOW!

A
Allysa J.
Absolutely amazing

I lost a filling a month ago and the wait to get a new one is insane. Ive read abou this stuff so I ordered it i was a little nervous because it is a little spendy but holy crap it is worth EVERY PENNY. Not only is my tooth not hurting but its gotten ride of other pain I was having.

B
Brooke H.
Healed cavity

After my 9 year old lost a filling, I tried this instead of scheduling dentist appointment since he wasn't hurting. At his next check up, dentist said no cavity or need to replace the filling. We all now use this several times a week. It is pricey but works.

J
James M.
Really works!

Great product, does what it claims, highly recommend!

T
Teresa M.
It works

I was told I had 3 cavities, so I bought this product. Cavities are gone!!! and my dentist yesterday said my check up was excellent. Everyone needs this product!

D
Dr R.
Now this is innovation

I'v been in holistic dentistry for about 8 years now after spending 6 in traditional practice, so I've seen my share of oral care products come and go. Most of them are fine. This one is different.

Honestly, the formulation blew me away. Whoever built this understands oral chemistry at a level that's beyond standard dental training and I don't say that lightly. It's not just throwing hydroxyapatite into a tube and calling it a day. The whole thing is designed around pH optimization so the nHAp actually binds to enamel, and because it's a leave-on serum, it keeps working after you spit it out. That matters more than people realize.

I was a bit cautious about the 30% nHAp concentration at first. Typically, you don't need much beyond 10%. But once I understood how the formula works with a stable PH, and fully suspended ingredients the higher concentration actually makes sense clinically.
What really got me was the arginine bicarbonate. That's not your standard L-arginine. It's a separately manufactured compound that drives the pH environment to push minerals into enamel. Pair that with the xylitol and zinc at what appear to be very intentional dosages, and nothing here feels like filler.

I did my own homework on science. About 40 clinical trials cited, and everything I checked held up. I'm now giving this to my patients.

At this price point with a180-day guarantee? I'm genuinely surprised it's not three times the cost.

If you're serious about stronger enamel, fewer cavities, and actually taking care of your mouth the right way and not only masking problems you need to be using this. As a dentist, I don't recommend things I haven't vetted myself. I vetted this one thoroughly, and it's now part of my practice. That should tell you everything you need to know

Hi Dr. Allen,

Thank you so much for sharing your detailed experience and kind words! We're thrilled to hear that our enamel-GEN serum meets your high standards and has become a valuable part of your practice. Your trust and thorough evaluation mean a lot to us. We're committed to supporting your mission for better oral health!

Best regards,
The Basis Oral Team

A
Ang H.
The miracle serum

I took a gamble on tying to enamel gen. At first I bought 1 bottle to try it after being told I had 3 cavites that needed to be filled. I liked it after the first bottle so decided to take the buy 2 get 1 free special to see what it could do for my 3 cavities if I used it consistenty. For the next 90 days I used it 2 times a day. When I finished I scheduled my next dentist appointment. I had moved during this process so it was a new dentist I went to for the first time. When he did the X-ray he said my teeth looked great. I asked him what about the cavities. He said what cavitites? I dont see anything. The biggest surprise of my life!! I was shocked at what this stuff can do, I will never stop using this.

This is an incredible story. Glad we could help you out.

R
Rebecca F.
The Best!

My experience has been something I have been sharing since week 2. It burned the first few times I used it. It went away by the 3rd or 4th application. That's around the time I noticed the sensitivity on my back teeth going away. After about 2 weeks, I couldn't feel much anymore. It's about 2 month in and cold drinks and foods aren't a challenge for me anymore. Its been a relief to finally find something I know will always work.

J
Joyce
No more concerns

I am a woman going through that mid 40's hormonal shift and it hard. The couple of years I went from having pretty good luck with cavitites and dental work until a couple year ago. Everything went wrong, my teeth started losing there white and got this nasty yellow, my mouth was alway dry and my breath now needs a mint at all times. it went from worry to panic because it only got worse. The dentist wasnt a lot of help, he just said my tooth enamel was thinning and to keep trying to eat healthy and I could slow down enamel loss. I started usign enamel gen around 7 months ago and immediately noticed my mouth was not dry anymore, and my breathe felt clean all day long, not the clean you get from mints but clean after a brushing feeling. That happened after the first time using it. Within about a month I started to notice the yellowing starting to turn back to a white color. Now, my teeth look like they did 10 years ago and my breath issue and dry mouth are nowhere to be found. I wish the product has a stronger mint taste but its been amazing so far.

K
Kelly M.
A great find

When I say it works, it works more than what they claim. This stuff should be promoted by every dentist. Not only are my teeth cavity free after using it for a year, my mouth feels clean, I have literally no plaque forming on my teeth and they seem to get stronger each month I stay committed to using enamel GEN. It started as a test to see if it worked, I never miss an application now. Its more important than my skin care routine and does so much more.

I
Isabel
Try it

When your someone who always seems to have a cavity it gets depressing. Every year there is at least 1 more to get filled. 2026 has been my year. I stated enamel-GEN Dec 2025. I had my first dentist visit in May and no new cavities and nothing to monitor. Thank YOU

B
Brenda F.
What do I do with this?

I just received my enamel gen in the mail with no instructions or guide of any kind! What am I supposed to do? They leave how to apply and how often and saftety precautions to the wind. I don't even have an easy way to contact these people. Bad business.

Hi Brenda, we're glad you reached out for help on Facebook! Our team was able to respond within an hour and even had our co-founder, Chris, create a personalized walkthrough video so you could start using your Enamel-GEN right away. We hope it helped!

C
Chris
WOW

This stuff has my teeth so white my says it looks like I have dentures. I had to get the est of my family using it like me

D
Deborah A.
Fast Relief

Sensitive tooth calmed in a few applications. Only a 4 because I don't know how long the relief lasts. If this lasts, this is a 5-star product.

J
James M.D.
All the right ingredients

Time will tell whether this product is formulated well to help strengthen tooth health. I purchased this product because it has all the ingredients for tooth recovery over time.

R
Rose D.
Keeping my teeth because of this product enamel-GEN!

I think this product works great. It really seems to have strengthened two broken molars in the furthest back of my mouth. One broke quite a lot, and I was eating soft foods for a while 'til I could find a dentist to pull the tooth. It works so well that I have been able to keep the tooth and for the most part chew normally again. I regularly buy this product. Combined with baking soda and enamel-GEN my mouth is in pretty good shape considering all the work I would normally need done. Very happy with this product.

N
Nancy W.
You gotta try it

So far so good. No sensitivity. I need to continue using to see if it's improving my tooth enamel.

J
Jim M.J.I.
Sensitive teeth? Try this!

Yes it is a bit costly but it worked GREAT for me. My molars were very sensitive & causing me pain & grief. By the 2nd day of using this the sensitivity was gone completely and has not come back. SO relieved.

L
Liz L.
Wish I found this sooner for sensitive teeth!

I've struggled with sensitive teeth for almost 15 years. But as I've gotten older, it's progressively gotten worse. My dentist kept encouraging Sensodyne, but it's slowly not been helping. These drops have made a dramatic difference in just a week! I don't dread brushing my teeth and I'm not as nervous to try cold foods. Excited to see how it continues to help heal my teeth!

J
John K.
Works well

Arrived as expected and on time. Second purchase. It really reduces sensitivity after just a few uses. Important to brush in.

A
Anonymous
Pretty good

I did like the use of this product and I noticed a difference.

A
Anonymous
AWESOME

Works awesome. I have 2 spots on my front top teeth that needed filled but I just haven't had time to get them done but this is actually fixing them. It's obviously not a quick fix but you can tell within a couple weeks that it’s working.

A
Anonymous
Works

I had a toothache and didn't have time to see a dentist for a week. This was a quick delivery so figured why not try, I'm going to the dentist anyways what's it going to hurt? Well, I didn't have to go to the dentist but went anyway without my toothache, and the dentist could see nothing wrong.

A
Anonymous
excellent Product

I am new to this product but seems as advertised... very good...

A
Anonymous
Helping my teeth

This product is helping my teeth sensitivity, it's helping my teeth to look whiter, feel cleaner.

S
Sonya P.
Works!!!

All I know is this stuff works and it works VERY well. After one use, the sensitivity in my teeth lessened significantly. After one week's use, my teeth are stronger, no sensitivity to cold and hot, whitens slightly, but it's worth it. I feel the difference and it is totally worth the price. I will DEFINITELY purchase again.

A
Anonymous
Who knows

It's only been a week since I started the product but I was very curious about it. It claims to get rid of cavities and so far it seems to be working so who knows!

C
Charles A.V.J.
Great customer service!!! Great product!!!

I originally ordered enamel-GEN through Amazon. It was recommended by my dentist and the research is sound. There had been a delay in shipping due to a FedEx misrouting... Medicinal Foods continued to maintain contact and keep the customer priority. Not only is the enamel-GEN product great, their customer service is friendly, helpful and quick to respond. I highly recommend and will definitely order enamel-GEN again but probably directly from the go.tryenamel-GEN.com website.